Thrift is popular and it "supports" more targets, but I found a lot of bugs in some of its lesser-known implementations. This may not be an issue if you're using a widely-used Thrift platform, but if you're choosing Thrift because it supports the target you want while another RPC doesn't, do watch out for weird bugs and issues.

I haven't tried to use Protobufs or gRPC in a serious way so I can't say if it's better or worse, but I would hope it supports fewer targets because it takes stability and QC more seriously.