Hacker Newsnew | past | comments | ask | show | jobs | submitlogin

> "We have viable treatments that work and could be prescribed en masse. Not discussed, not mentioned."

Can you explicitly mention what those treatments are? I'm genuinely curious.



There are various antiviral drugs which are orders of magnitude more expensive, have mediocre efficacy and a worse side effect profile compared to any of the main vaccines, and must be started within days of initial infection to work properly.

They are a great addition (besides vaccines and non-pharmaceutical public health measures) for treating high-risk patients for whom the vaccines don’t provide perfect protection (e.g. the very elderly and immune compromised), but a poor primary response.


[flagged]


The Cochrane Reviews are regarded as one of the preeminent collections of systematic reviews in medicine. They conclude that “overall, the reliable evidence available does not support the use of ivermectin for treatment or prevention of COVID‐19 outside of well‐designed randomized trials.”

https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD...

A similar conclusion regarding lack of evidence is discussed in NIH treatment guidelines:

https://www.covid19treatmentguidelines.nih.gov/therapies/ant...

In line with consensus in the field, ivermectin is not contained among the treatment guidelines of any institution at which I have practiced.


We just had an article about this. I am loath to link to Scott Alexander, but it's the most likely thing to persuade HN users. https://astralcodexten.substack.com/p/ivermectin-much-more-t...


How come? Why do you loath to link to his writings?


Why point out that you loathe someone before linking their work? What an odd, pompous thing to say.


loath ≠ loathe

loath is an adjective meaning reluctant. loathe is a verb meaning disgust/hate.


Ugh, silly mistake on my part.


Ivermectin has been shown over and over to be no better than placebo. Sure it has it's uses but covid ain't one of them.


We have excellent outcomes with monoclonal antibody-based drugs (the expensive route). Monoclonal is interesting because we may be able to take it preemptively. We have excellent results with steroids, vitamins, weight loss and exercise (low cost).

One way to search (and ignore random people like myself) for this, is to look for different countries treatment protocols (they are often published into other languages). There is a lot of serious people working hard trying to find good solutions.


Here are the latest COVID-19 treatment guidelines. They are very effective in preventing deaths when applied early and aggressively. Unfortunately many patients wait too long before seeking care, and many physicians still don't follow the protocol.

https://www.covid19treatmentguidelines.nih.gov/about-the-gui...


The anti-covid pill from Pfizer looks impressive:

https://www.science.org/content/blog-post/pfizer-s-good-news...


I thought I remember reading something early on about protease inhibitors and COVID, cool to see that is coming out now.




Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: