It can be a bit fussy, but works well --- unfortunately, there hasn't really been a vector drawing program focused specifically on stylus use since Futurewave Smartsketch (which became Flash by way of Futuresplash Animator).
Some operations are best with keyboard (i.e. moving, zooming, panning, duplicating, acessing panels) and you need modifier keys quite often. You can map one or two to the stylus buttons, but that may not be sufficient
I really hope it does, but for now it lacks in the basics such as panning (Krita can hold down a button + move pen to pan the canvas), button support (I don't think there's a way to map pen buttons to specific functions, let alone switch between them), and the drawing tools are still really basic. They are focusing on UX for the next release though, and UX issues can be discussed in the Inkscape UX Gitlab repo.