I enable all the "green" recommend options, then go back and re-enable location services, because I like having those for weather and setting the clock automatically.
The one trick I figured out is that things are split between the "Current User" and "Local Machine" tabs, and I have to enable the Location Services on both.
I've never figured out how to best use O&O ShutUp10 so I can use it without constantly having to figure out why something stopped working.
Do you have a setup you'd recommend?