I generally reply openly about my ten-year plan, I promise that it's going to change, and I restate how large a challenge it is to maintain excitement and interest at their company for the next ten years of my life.
I feel that either you misunderstood me or I misunderstand you. I'm leaning towards the first option.
By which I mean - There's a distinction between the kind of interview that happens between a founder and an investor and the one that happens between an employee and an employer. I wouldn't be surprised if an investor asked that kind of question, but if an employer did, I would think it was rather arrogant.